Zhe Sage Chen

Associate Professor of Psychiatry, Neuroscience and Physiology
New York University, School of Medicine


I am a principal investigator at New York University School of Medicine (NYUSOM), where I direct the Computational Neuroscience, Neuroengineering and Neuropsychiatry (CN3) Laboratory. I am the co-director of Computational Psychiatry Program at the NYU Department of Psychiatry. I am also a faculty member of the Training Program of Computational Neuroscience at NYU and an affiliated faculty member of the Neuroscience Institute at NYUSOM, and associated faculty in the Department of Biomedical Engineering at the NYU Tandon School of Engineering.

I am a computational neuroscientist and an electrical engineer. My work has focused on using statistical/biophysical modeling, computational statistics, and machine learning methods to help understand representations of neuroscience data, to decipher important neural circuit mechanisms of targeted brain circuits, such as the hippocampus, prefrontal cortex, and motor cortex of rodents and non-human primates. In collaboration with experimental neuroscientists, my team has developed real-time brain-machine interfaces to conduct closed-loop neuroscience experiments, such as detecting acute pain signals for acute pain signals for pain neuromodulation, and decoding animal’s trajectory paths during off-line memory reactivation. Finally, I have been gradually building my research portfolio along the direction of computational psychiatry and translational neuroscience, aiming to bridge the gap between animal and human research.

My current and future research directions focus on the intersection of computational and systems neuroscience, neural engineering, and data science.


11/2021 – present

Associate Faculty
New York University Tandon School of Engineering
Department of Biomecical Engineering

09/2018 – present

Associate Professor
New York University School of Medicine (NYUSOM)
Department of Psychiatry
Department of Neuroscience & Physiology

04/2014 – 09/2018

Assistant Professor
New York University School of Medicine (NYUSOM)
Department of Psychiatry
Department of Neuroscience & Physiology

04/2014 – present

Computational Neuroscience, Neuroscience Institute, NYUSOM

06/2017 – present

Training Program in Computational Neuroscience, NYU


2015 – 2021

Neural Networks (official journal of International Society of Neural Networks)

2017 –

Journal of Neural Engineering

2020 –

Frontiers in Computational Neuroscience


Frontiers in Psychiatry (Cognition)


IEEE Transactions on Neural Systems and Rehabilitation Engineering

Guest Editor
Computational Intelligence and Neuroscience
Frontier in Computational Physiology
Journal of Computational Neuroscience